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Drug Profile, Expanded Targeted Panel by LC-MS/MS, Serum/Plasma
Ordering Recommendation
Use to detect drug exposure from among a targeted list of prescriptions, over-the-counter medications, and illicit drugs; for a complete list of drugs and drug metabolites detected, refer to Additional Technical Information. Not recommended to determine medication compliance or to assess for undisclosed drug/substance use in the context of pain management, substance use disorder treatment, or any other pharmacotherapies involving controlled substances.
New York DOH Approval Status
Specimen Required
Plain red (no additives, serum gel or SST tubes are not acceptable), gray top (NaF/oxalate), lavender (K2 or K3EDTA) or pink (K2EDTA).
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 4 mL of serum or plasma into an ARUP standard transport tube. (Min: 2 mL)
Refrigerated.
Gel separator tubes or light blue (sodium citrate). Specimens exposed to repeated freeze/thaw cycles. Postmortem specimens.
After separation from cells: Ambient: 24 hours; Refrigerated: 2 weeks; Frozen: 2 months.
Methodology
Qualitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Mon, Fri
Reported
1-8 days
Reference Interval
By report
Interpretive Data
The qualitative drug panel can detect 127 drugs and drug metabolites by LC-MS/MS. The absence of expected drug(s) and/or drug metabolite(s) may indicate noncompliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, or limitations of testing. The concentration at which the test can detect a drug or metabolite varies within a drug class. The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.
This assay is for medical purposes only; not valid for forensic use
For a complete list of drugs and drug metabolites detected, refer to the Additional Technical Information.
Laboratory Developed Test (LDT)
Note
If a drug class is reported as present, the test will report the specific drug present from the drug class. (Classes include ARUP test codes 3005045, 3005046, 3005047, 3005048, 3005049, 3005050, 3005051, 3005052, 3005053, 3005054, 3005055, 3005056, 3005057, 3005058, or 3005059.)
Hotline History
CPT Codes
80323; 80326; 80329; 80334; 80337; 80338; 80341; 80344; 80346; 80348; 80353; 80354; 80356; 80357; 80358; 80359; 80360; 80361; 80363; 80365; 80366; 80368; 80370; 80371; 80372; 80373; 80377; 83992 (Alt code: G0482)
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 3004834 | Anticoagulants, Serum/Plasma | |
| 3004835 | Antihistamines, Serum/Plasma | 80197-7 |
| 3004836 | Cardiac, Serum/Plasma | |
| 3004837 | Anticonvulsants, Serum/Plasma | |
| 3004838 | Antidepressants, Serum/Plasma | |
| 3004839 | Antipsychotics, Serum/Plasma | |
| 3004840 | Nicotine, Serum/Plasma | 61128-5 |
| 3004841 | Opioids, Serum/Plasma | |
| 3004842 | Cough Suppressants, Serum/Plasma | 3538-6 |
| 3004843 | NSAIDs, Serum/Plasma | 3297-9 |
| 3004844 | Benzodiazepines, Serum/Plasma | |
| 3004845 | Muscle Relaxants, Serum/Plasma | |
| 3004846 | Sedative-Hypnotics, Serum/Plasma | 33040-7 |
| 3004847 | Stimulants, Serum/Plasma | |
| 3004848 | Antidiabetics, Serum/Plasma |
Aliases
- Blood screen
- Comprehensive drug screen
- Drug analysis
- General toxicology
- Multiple drug analysis
- Tox screen
